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Medical laboratory scientist (MLS) certification examination offered by the ASCP Board of Certification (BOC) is composed of 100 examination questions given in a 2 hour 30 minute time frame. All examination questions are multiple-choice with one best answer. The MLS (ASCP) certification examination is administered using the format of computer adaptive testing (CAT).

The certification examination questions encompass different subtests within the area of Medical Laboratory Science: Blood Banking, Urinalysis and Other Body Fluids, Chemistry, Hematology, Immunology, Microbiology, and Laboratory Operations. Each of these subtests comprises a specific percentage of the overall 100-question certification examination.

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